Immediately discontinue if allergic or anaphylactic reaction occurs; at 1st clinical signs of CV overload (headache, dyspnoea, jugular vein congestion), or increased BP, raised venous pressure & pulmonary oedema. Hypervolaemia or haemodilution especially in patients w/ decompensated cardiac insufficiency, HTN, oesophageal varices, pulmonary oedema, haemorrhagic diathesis, severe anaemia, renal & post-renal anuria. Carefully monitor against circulatory overload & hyperhydration; electrolyte status. Do not dilute w/ water for inj. Pregnancy & lactation. Childn.